A selected list of publications...
Cardiovascular
Xin Zeng; J. Luis Guerrero; Adam Kozak; Gavin Braithwaite; Robert A. Levine; Gus J. Vlahakes; Judy Hung. "Application of polymer-mesh device to remodel left ventricular–mitral valve apparatus in ischemic mitral regurgitation," The Journal of Thoracic and Cardiovascular Surgery, April 2018, Volume 155, Issue 4, Pages 1485–1493. https://www.jtcvs.org/article/S0022-5223(17)32485-6/fulltext
Zeng X, Zou L, Levine RA, Guerrero JL, Handschumacher MD, Sullivan SM, Braithwaite GJ, Stone JR, Solis J, Muratoglu OK, Vlahakes GJ, Hung J.; "Efficacy of Polymer Injection for Ischemic Mitral Regurgitation: Persistent Reduction of Mitral Regurgitation and Attenuation of Left Ventricular Remodeling," JACC: Cardiovascular Interventions 2015 (in press) http://www.ncbi.nlm.nih.gov/pubmed/25596792
Solis, J.; Levine, R.A.; Johnson, B.; Guerrero, J.L.; Handschumacher, M.D.; Sullivan, S.; Lam. K.; Berlin, J.; Braithwaite, G.J.; Muratoglu, O.K.; Vlahakes, G.J.; Hung, J.; "Polymer injection therapy to reverse remodel the papillary muscles: efficacy in reducing mitral regurgitation in a chronic ischemic model," Circulation, Cardiovascular Interventions 2010, 3(5) 499-505 http://www.ncbi.nlm.nih.gov/pubmed/20736444
Hung, J.; Solis, J.; Luis Guerrero, J.; Braithwaite, G. J. C.; Muratoglu, O. K.; Chaput, M.; Fernandez-Friera, L.; Handschumacher, M. D.; Wedeen, V. J.; Houser, S.; Vlahakes, G. J.; Levine, R. A. "A Novel Approach for Reducing Ischemic Mitral Regurgitation by Injection of a Polymer to Reverse Remodel and Reposition Displaced Papillary Muscles," Circulation 2008, 118, S263-269. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981105/
Chromatography
Claire Guest; Rob Harris; Karen S. Sfanos; Eva Shrestha; Alan W. Partin; Bruce Trock; Leslie Mangold; Rebecca Bader; Adam Kozak; Scott McLean; Jonathan Simons; Howard Soule; Thomas Johnson; Wen-Yee Lee; Qin Gao; Sophie Aziz; Patritsia Maria Stathatou; Stephen Thaler; Simie Foster; Andreas Mershin. "Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer." PLoS ONE 16(2): e0245530. February 17, 2021.
https://doi.org/10.1371/journal.pone.0245530
Orthopaedics
Louis G. Malito; Sofia Arevalo; Adam Kozak; Stephen Spiegelberg; Anuj Bellare; Lisa Pruitt. "Material properties of ultra-high molecular weight polyethylene: Comparison of tension, compression, nanomechanics and microstructure across clinical formulations," Journal of the Mechanical Behavior of Biomedical Materials, Volume 83, July 2018, 9-19.
https://www.sciencedirect.com/science/article/pii/S1751616118304077
Braithwaite GJ, Daley MJ, Toledo-Velasquez D. "Rheological and molecular weight comparisons of approved hyaluronic acid products - preliminary standards for establishing class III medical device equivalence." Journal of Biomaterials Science, Polymer Edition 27(3) 235-246 (2016). http://www.tandfonline.com/doi/abs/10.1080/09205063.2015.1119035 (Open Access)
Emily G. Heuer, Gavin J. C. Braithwaite, Bayen L. Miller, Stephen H. Spiegelberg, Ray A. Gsell, Alicia S. Rufner and Norman Stark. "Oxidative-induction time as a measure of vitamin E concentration in ultra-high molecular weight polyethylene," Journal of Biomedical Materials Research Part B: Applied Biomaterials, April 28, 2014. http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33175/abstract
Spiegelberg, S.H., "UHMWPE for Total Joint Arthroplasty: Past, present and future," Bonezone, June 9, 2012.
http://www.bonezonepub.com/component/content/article/453-uhmwpe-for-total-joint-arthroplasty-past-present-and-future?limitstart=0
H. Bodugoz-Senturk, J. Choi, E. Oral, J.H. Kung, C.E. Macias, G. Braithwaite and O.K. Muratoglu (2008) “The effect of polyethylene glycol on the stability of pores in polyvinyl alcohol hydrogels during annealing,” Biomaterials 29, 2, 141-149 http://www.ncbi.nlm.nih.gov/pubmed/18996584
Muratoglu, O.K., Ruberti, J., Melotti, S., Spiegelberg, S.H., “Optical analysis of surface changes on early retrievals of highly cross-linked and conventional polyethylene tibial inserts,” J Arthroplasty, 18 (7), 42-47 (2003). http://www.ncbi.nlm.nih.gov/pubmed/14560410
Kurtz, S.M., Muratoglu, O.K., Gsell, R., Greer, K,. Shen, F.W., Cooper, C., Buchanan, F.J., Spiegelberg, S.H, Yau, S.S., Edidin, A.A., “Interlaboratory validation of oxidation-index measurement,” Journal of Biomed. Mater. Res., 63, 15-23, (2002). http://www.ncbi.nlm.nih.gov/pubmed/11787024
Kurtz, S.M., Muratoglu, O.K., Buchanan, F., Currier, B., Gsell, R., Greer, K., Gualtieri, G., Johnson, R., Schaffner, S., Sevo, K., Spiegelberg, S.H., Yau, S., Shen, F., "Interlaboratory reproducibility of standard accelerated aging methods for oxidation of UHMWPE," Biomaterials, 22, 1731-1737 (2001). http://www.ncbi.nlm.nih.gov/pubmed/11396876
Miscellaneous Biomaterials
Saleh A. Alageel; Samer N. Arafat; Borja Salvador-Culla; Paraskevi E. Kolovou; Khadijeh Jahanseir; Adam Kozak; Gavin J. C. Braithwaite; Joseph B. Ciolino. "Corneal Cross-Linking With Verteporfin and Nonthermal Laser Therapy," Cornea. 2018 Mar; 37(3):362-368. https://insights.ovid.com/pubmed?pmid=29176450
Berlin, J., Braithwaite, G., Spiegelberg, S.,"Injectable hydrogel-based medical devices: There's always room for Jell-O," BONEZONE, Fall, 2010. http://www.bonezonepub.com/component/content/article/247-injectable-hydrogel-based-medical-devices-theres-always-room-for-jell-o1?limitstart=0
Extensional Rheology
Spiegelberg, S., McKinley, G."Non-Newtonian Flows: Elongational Flows," Handbook of Experimental Fluid Dynamics, Tropea, Foss & Yarin (eds), Springer-Verlag, New York (2007).
Yao, M., Spiegelberg, S.H., and McKinley, G.H., “Fluid Dynamics of Weakly Strain-Hardening Fluids in Filament Stretching Devices,” J. Non-Newtonian Fluid Mech., 89, 1-43 (2000). http://web.mit.edu/nnf/publications/GHM43.pdf
Anna, S.L., Spiegelberg, S.H. and McKinley, G.H., “Elastic Instability in Elongating Fluid Filaments,” Phys. Fluids (Gallery of Fluid Motion), 9, p. 10, (1997). http://web.mit.edu/nnf/publications/GHM25.pdf
Doyle, P., Shaqfeh, E.S.G., Spiegelberg, S.H. and McKinley, G.H., “Relaxation of Dilute Polymer Solutions Following Extensional Flow,” J. Non-Newtonian Fluid Mech., 76, 79-110 (1998). http://www.ingentaconnect.com/content/els/03770257/1998/00000076/00000001/art00113
Pakdel, P., Spiegelberg, S.H., and McKinley, G.H., "Cavity Flow of Elastic Liquids; Two-dimensional flows," Physics of Fluids, 9, 3123-40 (1997). http://pof.aip.org/resource/1/phfle6/v9/i11/p3123_s1
Spiegelberg, S.H. and McKinley, G.H., "Stress Relaxation and Elastic Decohesion of Viscoelastic Polymer Solutions in Extensional Flow," J. Non-Newtonian Fluid Mech., 67, 49 (1996). http://www.sciencedirect.com/science/article/pii/S0377025796014759
Spiegelberg, S.H., Ables, D.C., and McKinley, G.H., "The Role of End-Effects on Measurements of Extensional Viscosity in Filament Stretching Rheometers," J. Non-Newtonian Fluid Mech., 64, 229 (1996). http://www.sciencedirect.com/science/article/pii/0377025796014395
Colloids and Surfaces
G. Braithwaite and G. McKinley (1999) "Microrheometry for Studying the Rheology and Dynamics of Polymers near Interfaces", Journal of Applied Rheology, 9, 27-33. http://web.mit.edu/nnf/publications/GHM37.pdf
G.J.C. Braithwaite and Paul F. Luckham (2002) “The Simultaneous Determination of the Forces and Viscoelastic Properties of Adsorbed Polymer Layers.” Journal of Colloid and Interface Science, 218, 1, 97-111 http://www.ncbi.nlm.nih.gov/pubmed/10489283
G.J.C. Braithwaite, P.F. Luckham, A.M. Howe (1999) “Study of a Solvated Adsorbed Gelatin Layer Using a Modified Force Microscope.” Journal of Colloid and Interface Science, 213, 2 525-545 http://www.ncbi.nlm.nih.gov/pubmed/10222094
G. J. C. Braithwaite and P. F. Luckham (1997) "Effect of Molecular Weight on the Interactions between Poly(ethylene Oxide) Layers adsorbed to Glass Surfaces", Journal of the Chemical Society, Faraday Transactions, 93, 1409-1415. http://pubs.rsc.org/en/content/articlelanding/1997/FT/a606976b
P. Luckham, G. Braithwaite and A. Howe (1997) "Interactions between adsorbed gelatin layers." Imaging Science Journal, 45, 223.
G. Braithwaite, P. Luckham, A. Meurk and K. Smith (1997) "Probing Colloidal Interactions Using Modified Atomic Force Microscopy" In Modern Aspects of Colloidal Dispersions: Results from the DTI Colloid Technology Programme (Eds, Ottewill, R. H. and Rennie, A. R.) Kluwer Academic Publishers, Dordrecht.
Medical Device Cleanliness
Spiegelberg, S., “ASTM Standards for Assessing Cleanliness of Medical Devices,” Journal of ASTM International, in press (2006).
Spiegelberg, S., “ASTM Activities for Assessing Cleanliness of Medical Devices,” Proceedings from the Materials & Processes for Medical Devices Conference, p. 125, Sept 8-10, ASM International (2004). http://www.astm.org/DIGITAL_LIBRARY/JOURNALS/JAI/PAGES/JAI13389.htm